Chronic insulin analogue treatment does not affect the mutational profile of the tumors. A) The average number of point mutations per treatment group. B) The average number of frame shifts per treatment. C) The average number of start CODON insertions per treatment. D) The average number of stop CODON insertions per treatment. (TIF 12348 kb
Initial tumor size, extended BGJ398 treatment, and dimerizer injection have no significantly effect ...
Breast cancer cell viability dose curves in response to SKI-II. Refer to Fig. 5 for experimental det...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...
Figure S3. Reduced IGF-1R in primary tumors does not alter the active T cell population. (A, B) Quan...
Immunohistochemistry and manual scoring analysis of Australian Breast Cancer Tissue Bank patient sam...
Figure S1. IMC-A12 blocks activation of IGF-1R signaling. Western blot analysis of pAkt (473) and pI...
Table S1. MMTV-Wnt1 tumor phenotype is altered with reduced IGF-1R [1]. (DOCX 16 kb
Figure S1. Comparison of somatic mutation frequency between IBC and non-IBC in four subgroups. (a) T...
Table S3. Cytokine and chemokine profile is altered in MMTV-Wnt1 tumors with attenuated IGF-1R. Gene...
Figure S5. Wnt2 and Frizzled9 expression are inversely correlated with IGF-1R expression in breast c...
OSI-906 inhibits p-IGF1R and IGF1R signaling factors in breast cancer cell-lines. 3 × 105 ER-positiv...
Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...
BGJ398 treatment in Wnt1/iR1 tumors results in rapid apoptosis of luminal cells and downregulation o...
Figure S2. Mutant PAPP-A decreases DDR2 activation by IGF-1: a) immunoblot of DDR2 and phospho-DDR2 ...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Initial tumor size, extended BGJ398 treatment, and dimerizer injection have no significantly effect ...
Breast cancer cell viability dose curves in response to SKI-II. Refer to Fig. 5 for experimental det...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...
Figure S3. Reduced IGF-1R in primary tumors does not alter the active T cell population. (A, B) Quan...
Immunohistochemistry and manual scoring analysis of Australian Breast Cancer Tissue Bank patient sam...
Figure S1. IMC-A12 blocks activation of IGF-1R signaling. Western blot analysis of pAkt (473) and pI...
Table S1. MMTV-Wnt1 tumor phenotype is altered with reduced IGF-1R [1]. (DOCX 16 kb
Figure S1. Comparison of somatic mutation frequency between IBC and non-IBC in four subgroups. (a) T...
Table S3. Cytokine and chemokine profile is altered in MMTV-Wnt1 tumors with attenuated IGF-1R. Gene...
Figure S5. Wnt2 and Frizzled9 expression are inversely correlated with IGF-1R expression in breast c...
OSI-906 inhibits p-IGF1R and IGF1R signaling factors in breast cancer cell-lines. 3 × 105 ER-positiv...
Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...
BGJ398 treatment in Wnt1/iR1 tumors results in rapid apoptosis of luminal cells and downregulation o...
Figure S2. Mutant PAPP-A decreases DDR2 activation by IGF-1: a) immunoblot of DDR2 and phospho-DDR2 ...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Initial tumor size, extended BGJ398 treatment, and dimerizer injection have no significantly effect ...
Breast cancer cell viability dose curves in response to SKI-II. Refer to Fig. 5 for experimental det...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...