Eupatilin reduces neural cell death and improves neurological function 3 days after tMCAO-challenge.

<p>Mice were challenged with tMCAO and effects of eupatilin (Eup, 10 mg/kg, a single administration, <i>p</i>.<i>o</i>.) on neural cell death and neurological function were assessed 3 days after tMCAO. (<b>A</b>) Representative images of FJB-stained sections (n = 5 per group). Diagram boxes display the cerebral area where the images in middle and bottom panels were acquired. Dashed lines indicate the lesion site. Scale bars, 200 μm (top panels) and 50 μm (middle and bottom panels). (<b>B</b>) Quantification of neurological score reflecting neurological functions. n = 5~6 per group. *<i>P</i><0.05 versus the vehicle-treated tMCAO group (tMCAO+veh).