Palladium-Catalyzed Double-Isocyanide Insertion via Oxidative N–O Cleavage of Acetyl Oximes: Syntheses of 2<i>H</i>‑Pyrrol-2-imines

The palladium-catalyzed reaction of acetyl oximes with isocyanides was developed for the synthesis of 2<i>H</i>-pyrrol-2-imines. The key steps were (i) generation of an enamido-palladium­(II) species, (ii) migratory double-isocyanide insertion, and (iii) cyclization. The scope of the synthesis of some 2<i>H</i>-pyrrol-2-imines was extended to the synthesis 1<i>H</i>-pyrrole-2,3-dione/1<i>H</i>-benzo­[<i>g</i>]­indole-2,3-dione derivatives via acid hydrolysis in a sequential one-pot manner