Optimality principles reveal a complex interplay of intermediate toxicity and kinetic efficiency in the regulation of prokaryotic metabolism - Fig 8

<p>(A) Excerpt of metabolic context of acetate and lipid <i>IV</i>_<i>A</i> biosynthesis. The green box highlights mechanisms of acetate toxicity. (B) lipid <i>IV</i>_<i>A</i> biosynthetic pathway including key characteristics (lower log IC50 values indicate higher toxicity).