Effects of FMN on hepatic expression of Nrf2 and antioxidative genes.

<p>(A, B) The expression of Nrf2 protein in mice liver, as determined by western blot. β-actin was calibrated. (C) Nqo1, G6pdx, SOD2, Gpx1 and Cat mRNAs expression. mRNA expression was determined by real-time PCR. 18S rRNA was calibrated. Values represent the means ± SE; <i>n</i> = 4. (*) the APAP group <i>vs</i> control; (#) APAP+ 50 mg/kg or APAP+ 100 mg/kg <i>vs</i> the APAP group. NS, not significantly; #, < 0.05; ** or ##, <i>p</i> < 0.05; *** or ###, <i>p</i> < 0.001.