<p><b>(A)</b> Members of the let-7 family (schematic). <b>(B)</b> Down-regulation of expression of let-7 family miRNAs in microarray experiments was validated by RT-PCR (n = 3, *<i>P</i> < 0.05).</p
MicroRNAs (miRNA) are approximately 22-nucleotide noncoding RNAs that negatively regulate protein-co...
The heterochronic gene let-7 serves as a tumor suppressor microRNA by targeting various oncogenic pa...
In recent years, various RNA-based technologies have been under evaluation as potential next-generat...
miRNAs belong to a class of small non-coding RNAs which can modu-late gene expression. Disturbances ...
<p>(<b>A</b>). Transfection of pre-let7a miRNA induced upregulation of Let-7a expression in S1 cells...
<p><b>(A)</b> Luciferase assays of let-7 targeting effects on <i>LIN28</i>. Mutations were generated...
<p>(A) Quantitative RT-PCR analysis of the expression levels of let-7 miRNA in normal 3A6<sup>RWV</s...
miRNAs are short non-coding RNA that regulate gene expression at the post-transcriptional level by i...
MicroRNAs (miRNAs) are small non-coding RNAs capable of regulating gene expression at the translatio...
Chemotherapy resistance remains an important problem in the breast cancer clinic. The ability to pre...
AbstractMetastasis and resistance to therapy significantly contribute to cancer-related deaths. Grow...
The implication of the let-7 family in cancer development is multifaceted. The family acts as tumor ...
textabstractMany microRNAs (miRNAs) target mRNAs involved in processes aberrant in tumorigenesis, su...
Metastasis and resistance to therapy significantly contribute to cancer-related deaths. Growing body...
microRNAs play a critically important role in a wide array of biological processes including those i...
MicroRNAs (miRNA) are approximately 22-nucleotide noncoding RNAs that negatively regulate protein-co...
The heterochronic gene let-7 serves as a tumor suppressor microRNA by targeting various oncogenic pa...
In recent years, various RNA-based technologies have been under evaluation as potential next-generat...
miRNAs belong to a class of small non-coding RNAs which can modu-late gene expression. Disturbances ...
<p>(<b>A</b>). Transfection of pre-let7a miRNA induced upregulation of Let-7a expression in S1 cells...
<p><b>(A)</b> Luciferase assays of let-7 targeting effects on <i>LIN28</i>. Mutations were generated...
<p>(A) Quantitative RT-PCR analysis of the expression levels of let-7 miRNA in normal 3A6<sup>RWV</s...
miRNAs are short non-coding RNA that regulate gene expression at the post-transcriptional level by i...
MicroRNAs (miRNAs) are small non-coding RNAs capable of regulating gene expression at the translatio...
Chemotherapy resistance remains an important problem in the breast cancer clinic. The ability to pre...
AbstractMetastasis and resistance to therapy significantly contribute to cancer-related deaths. Grow...
The implication of the let-7 family in cancer development is multifaceted. The family acts as tumor ...
textabstractMany microRNAs (miRNAs) target mRNAs involved in processes aberrant in tumorigenesis, su...
Metastasis and resistance to therapy significantly contribute to cancer-related deaths. Growing body...
microRNAs play a critically important role in a wide array of biological processes including those i...
MicroRNAs (miRNA) are approximately 22-nucleotide noncoding RNAs that negatively regulate protein-co...
The heterochronic gene let-7 serves as a tumor suppressor microRNA by targeting various oncogenic pa...
In recent years, various RNA-based technologies have been under evaluation as potential next-generat...