TNFα+CD40L-IFNγ- CD4+ T cells differ between fast and slow healers in Buruli ulcer disease.

<p>(<b>A</b>) BUD patients were divided into fast healers (≤ 111 days) and slow healers (> 111 days) based on the time required for complete healing and proportions of cytokine producing CD4+ T cells (<b>B</b>, <b>C</b>) or lesion sizes (<b>D</b>) are compared by non-parametric Mann Whitney <i>U</i> test. The healing rate within the first four weeks (in change if mm/week) was correlated with TNFα+CD40L-IFNγ- CD4+ T cells (<b>E</b>) by Spearman correlation or compared based on time until healing process starts after initiating antibiotic treatment (<b>F</b>).