Peripheral blood counts represented as average fold change in nude (a) and C57BL/6 (b) mice 3 and 5 days after ZOL treatment, respectively (n = 4 − 5/group). c CFU assay of bone marrow, peripheral blood and spleen 3 days after CTL or ZOL treatment; n = 5 nude mice/cohort, *p < 0.05. d BrDU-positive HSCs as a percentage of total HSCs per nude mouse femur at early time points post ZOL treatment; n.s. not significant; n = 5 mice/cohort, 1 femur per mouse. (PDF 986 kb
is a figure showing the effect of Bz treatment on serum uric acid, calcium, and phosphate. Mice aged...
Figure S1. Chemotherapy-induced niche contributes to the increase of ROS and apoptosis in HSCs. (a) ...
BACKGROUND: The bone-targeting agent zoledronic acid (ZOL) increases breast cancer survival in subse...
a Growth kinetics of tumors after injecting host nude mice subcutaneously with admixtures of MDA-MB-...
Flow cytometry cell-surface markers used to quantify indicated hematopoietic stem and progenitor cel...
Background: The bone-targeting agent zoledronic acid (ZOL) increases breast cancer survival in subse...
Figure S1. Zoledronate (ZOL) at the ÎźM level presents a dose-dependently inhibitory effect on cellu...
Figure S3. Zoledronic acid induces apoptosis of cervical cancer cells. The histograms show the propo...
Figure S5. Zoledronic acid acts through the MPAK- and PI3K/Akt-pathways related proteins of cervical...
Figure S4. Zoledronic acid arrests the cell cycle of cervical cancer cells. The histograms show the ...
Figure S2. Zoledronate (ZOL) at the ÎźM level presents a negative effect on matrix mineralization of...
is a figure showing in-vitro induction of HSPA1A (HSP70) and HSPB1 (HSP27) expression in Bz-treated ...
Figure S2. Zoledronic acid affects the cervical cancer cells with stemness phenotype. Approximately ...
Kinetics of HSPCs involved in the drug-only group. Normal C57/BL6J mice were given one-day therapy, ...
Figure S1. Change in blood cell counts after DEX administration. A) Actual blood cell counts at base...
is a figure showing the effect of Bz treatment on serum uric acid, calcium, and phosphate. Mice aged...
Figure S1. Chemotherapy-induced niche contributes to the increase of ROS and apoptosis in HSCs. (a) ...
BACKGROUND: The bone-targeting agent zoledronic acid (ZOL) increases breast cancer survival in subse...
a Growth kinetics of tumors after injecting host nude mice subcutaneously with admixtures of MDA-MB-...
Flow cytometry cell-surface markers used to quantify indicated hematopoietic stem and progenitor cel...
Background: The bone-targeting agent zoledronic acid (ZOL) increases breast cancer survival in subse...
Figure S1. Zoledronate (ZOL) at the ÎźM level presents a dose-dependently inhibitory effect on cellu...
Figure S3. Zoledronic acid induces apoptosis of cervical cancer cells. The histograms show the propo...
Figure S5. Zoledronic acid acts through the MPAK- and PI3K/Akt-pathways related proteins of cervical...
Figure S4. Zoledronic acid arrests the cell cycle of cervical cancer cells. The histograms show the ...
Figure S2. Zoledronate (ZOL) at the ÎźM level presents a negative effect on matrix mineralization of...
is a figure showing in-vitro induction of HSPA1A (HSP70) and HSPB1 (HSP27) expression in Bz-treated ...
Figure S2. Zoledronic acid affects the cervical cancer cells with stemness phenotype. Approximately ...
Kinetics of HSPCs involved in the drug-only group. Normal C57/BL6J mice were given one-day therapy, ...
Figure S1. Change in blood cell counts after DEX administration. A) Actual blood cell counts at base...
is a figure showing the effect of Bz treatment on serum uric acid, calcium, and phosphate. Mice aged...
Figure S1. Chemotherapy-induced niche contributes to the increase of ROS and apoptosis in HSCs. (a) ...
BACKGROUND: The bone-targeting agent zoledronic acid (ZOL) increases breast cancer survival in subse...