JNK activation in the eye disc is sufficient to induce non-autonomous glia overmigration.

<p>(A and B) pJNK expression (green) in Control (A) and <i>dpp</i>^blk><i>hep</i>^CA (B). Asterisk show increased pJNK expression. (C and D) pMad staining (green) in Control (C) and <i>dpp</i>^blk><i>hep</i>^CA (D). Arrows point towards overmigrating glia that does not show pMad activation. A’–D’ and A”–B” show a magnification from the inset on figure A to D respectively. (E) EdU staining (light blue) in <i>dpp</i>^blk><i>hep</i>^CA. E’ show magnification of overmigrating glia in red and E” show a magnification of EdU staining in grey. Blue dashed line surrounds overmigrating glia. Glial cells stained with repo are shown in red. A yellow dashed line represents the MF. Scale bars correspond to 10 μm. (F) Graph showing the percentage of EdU positive glial cells in Control in <i>dpp</i>^blk><i>hep</i>^CA total and <i>dpp</i>^blk><i>hep</i>^CA overmigration (glia anterior to MF).