<p>Data are shown as means ± S.D. (n = 4–5). The inset figures show the plasma concentration-time profiles up to 2 h.</p
<p>Chromatogram was shown in (a) for blank plasma, (b) for plasma with 5-FU and 5-Bru, and (c) for s...
Mean plasma concentration-time profiles for CVD after oral administration of a single dose (1 mg/kg)...
A. Radioactivity levels (dpm mL-1) in mouse plasma determined by CRDS (triangles) and AMS (circles)....
<p>Pharmacokinetic parameters of carfilzomib after the intravenous administration of polymeric micel...
Carfilzomib-loaded polymeric micelles (CFZ-PM) based on poly(ethylene glycol)-b-poly(N-2-benzoyloxyp...
Carfilzomib (CFZ) is a peptide epoxyketone proteasome inhibitor approved for the treatment of multip...
Carfilzomib, an irreversible proteasome inhibitor, has a favorable safety profile and significant an...
<p>Plasma <b>concentration-time curves</b> of PF-05231023 in DIO mice following a single IV and SC a...
<p>Compounds were IP administered to fasted C57BL/6J mice at -30 min as described in the <a href="ht...
<p>Plasma was collected over a period of 15 minutes—48 hours after M10 injection and measured by ind...
<p>The plasma concentration-time profiles of Compound 1 after intravenous administration at 180 mg/k...
<p>Mean plasma concentration-versus-time curve of 7c and 7m after oral administration at 25 mg/kg to...
<p>(A) LC-MS/MS analysis of BPR0L075 with chromatogram showing the retention time of internal standa...
<p>(<b>A</b>) Glibenclamide concentration in plasma from individual female (white bars) and male (gr...
<p>PK profiles of HC-070 after intravenous (A) and oral (B) administration in C57BL/6 mice. Plasma c...
<p>Chromatogram was shown in (a) for blank plasma, (b) for plasma with 5-FU and 5-Bru, and (c) for s...
Mean plasma concentration-time profiles for CVD after oral administration of a single dose (1 mg/kg)...
A. Radioactivity levels (dpm mL-1) in mouse plasma determined by CRDS (triangles) and AMS (circles)....
<p>Pharmacokinetic parameters of carfilzomib after the intravenous administration of polymeric micel...
Carfilzomib-loaded polymeric micelles (CFZ-PM) based on poly(ethylene glycol)-b-poly(N-2-benzoyloxyp...
Carfilzomib (CFZ) is a peptide epoxyketone proteasome inhibitor approved for the treatment of multip...
Carfilzomib, an irreversible proteasome inhibitor, has a favorable safety profile and significant an...
<p>Plasma <b>concentration-time curves</b> of PF-05231023 in DIO mice following a single IV and SC a...
<p>Compounds were IP administered to fasted C57BL/6J mice at -30 min as described in the <a href="ht...
<p>Plasma was collected over a period of 15 minutes—48 hours after M10 injection and measured by ind...
<p>The plasma concentration-time profiles of Compound 1 after intravenous administration at 180 mg/k...
<p>Mean plasma concentration-versus-time curve of 7c and 7m after oral administration at 25 mg/kg to...
<p>(A) LC-MS/MS analysis of BPR0L075 with chromatogram showing the retention time of internal standa...
<p>(<b>A</b>) Glibenclamide concentration in plasma from individual female (white bars) and male (gr...
<p>PK profiles of HC-070 after intravenous (A) and oral (B) administration in C57BL/6 mice. Plasma c...
<p>Chromatogram was shown in (a) for blank plasma, (b) for plasma with 5-FU and 5-Bru, and (c) for s...
Mean plasma concentration-time profiles for CVD after oral administration of a single dose (1 mg/kg)...
A. Radioactivity levels (dpm mL-1) in mouse plasma determined by CRDS (triangles) and AMS (circles)....