Probucol ameliorates apoptosis in hyperoxic lung injury.
- Tomonobu Kawaguchi (3910612)
- Toyoshi Yanagihara (3910609)
- Tetsuya Yokoyama (1802488)
- Saiko Suetsugu-Ogata (3910615)
- Naoki Hamada (3910597)
- Chika Harada-Ikeda (3910600)
- Kunihiro Suzuki (3910603)
- Takashige Maeyama (3910606)
- Kazuyoshi Kuwano (768945)
- Yoichi Nakanishi (584819)
Publication date
April 2017
DOIAbstract
<p>(A-D) The effect of probucol on TUNEL staining. (A) No positive signals for TUNEL were observed in lung tissues of room-air-exposed mice treated with probucol. (B) There were some TUNEL-positive cells (arrows in F) in the lung tissues of hyperoxia-exposed mice. (C) Probucol treatment decreased the number of TUNEL-positive cells in hyperoxia-exposed mice. (D) Quantitative result of the number of TUNEL-positive cells in lung tissues. Original magnifications: ×200. Data are shown as the mean ± SEM from four mice in each group. **<i>p</i> < 0.01.</p
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