Additional file 9: Table S8. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Additional file 5: of Genome-wide analysis of DNA methylation in bronchial washings

Sang-Won Um (535627)
Yujin Kim (483088)
Bo Lee (3463586)
Dongho Kim (29790)
Kyung-Jong Lee (5237399)
Hong Kim (101826)
Joungho Han (483091)
Hojoong Kim (535625)
Young Shim (3463580)
Duk-Hwan Kim (483093)

May 2018

Table S3. The correlation between pack-years of smoking and DNA methylation in 53 control groups. (D...

Additional file 1: Table S1. of Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection

Yun Su (289202)
HongBin Fang (3511388)
Feng Jiang (95012)

October 2016

Differential cell percentages of stage I non-small cell lung (NSCLC) patients and smokers with benig...

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Symen Ligthart (701678)
Carola Marzi (236979)
Stella Aslibekyan (123439)
Michael Mendelson (2697424)
Karen Conneely (3448694)
Toshiko Tanaka (174638)
Elena Colicino (3503048)
Lindsay Waite (3503021)
Roby Joehanes (560601)
Weihua Guan (345071)
Jennifer Brody (174723)
Cathy Elks (3503054)
Riccardo Marioni (669892)
Min Jhun (3503015)
Golareh Agha (3503030)
Jan Bressler (248795)
Cavin Ward-Caviness (3503057)
Brian Chen (149932)
Tianxiao Huan (599733)
Kelly Bakulski (3503063)
Elias Salfati (3503045)
Giovanni Fiorito (136942)
Simone Wahl (112749)
Katharina Schramm (528479)
Jin Sha (847984)
Dena Hernandez (215322)
Allan Just (3448679)
Jennifer Smith (172056)
Nona Sotoodehnia (143373)
Luke Pilling (3503024)
James Pankow (160621)
Phil Tsao (3503066)
Chunyu Liu (9855)
Wei Zhao (14321)
Simonetta Guarrera (136940)
Vasiliki Michopoulos (3503051)
Alicia Smith (3448658)
Marjolein Peters (3503033)
David Melzer (202058)
Pantel Vokonas (587472)
Myriam Fornage (45591)
Holger Prokisch (26590)
Joshua Bis (711982)
Audrey Chu (3503069)
Christian Herder (44905)
Harald Grallert (72666)
Chen Yao (137375)
Sonia Shah (142603)
Allan McRae (3400103)
Honghuang Lin (560598)
Steve Horvath (28847)
Daniele Fallin (3503039)
Albert Hofman (107303)
Nicholas Wareham (153226)
Kerri Wiggins (3503018)
Andrew Feinberg (242567)
John Starr (231855)
Peter Visscher (3400094)
Joanne Murabito (3503036)
Sharon Kardia (3503060)
Devin Absher (217357)
Elisabeth Binder (3448661)
Andrew Singleton (23294)
Stefania Bandinelli (150002)
Annette Peters (62601)
Melanie Waldenberger (236985)
Giuseppe Matullo (136983)
Joel Schwartz (18324)
Ellen Demerath (198657)
AndrĂŠ Uitterlinden (3404267)
Joyce van Meurs (3404240)
Oscar Franco (2885594)
Yii-Der Chen (3503075)
Daniel Levy (51573)
Stephen Turner (3503027)
Ian Deary (489588)
Kerry Ressler (3503072)
JosĂŠe Dupuis (3503084)
Luigi Ferrucci (150038)
Ken Ong (448067)
Themistocles Assimes (746456)
Eric Boerwinkle (36288)
Wolfgang Koenig (26222)
Donna Arnett (192289)
Andrea Baccarelli (36523)
Emelia Benjamin (3503042)
Abbas Dehghan (174878)

December 2016

Significant methylation-expression results and corresponding expression-CRP results for the replicat...

Additional file 8: Table S7. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.05). (C...

Additional file 7: Table S6. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to COPD vs. smokers (Pâ<â0.01). (CSV 19 k...

Additional file 5: Table S4. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.01). (C...

Additional file 2: Table S1. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.001). (...

Additional file 3: Table S2. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to COPD vs. non-smokers (Pâ<â0.001). (CSV...

Additional file 1: Figures S1-S13. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

Figure S1.Boxplot shows distribution of pre-processed DNA methylation level (Î˛ values) from all the...

Additional file 1: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Table S1. (.MWD): DNA regions differentially methylated with COPD status in airway fibroblasts. Summ...

Additional file 3: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Figure S1. (.EPS): CpG methylation variation in parenchymal fibroblasts in COPD samples. A) Plot of ...

Additional file 1: Tables S1. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
André Amaral (3848719)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

Search terms (n = 92) used within MEDLINE, EMBASE and Web of Science. (DOCX 13 kb

Additional file 4: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Figure S2. (.EPS): GRIK2 methylation and expression do not correlate with smoking pack-years or smok...

Additional file 2: Tables S2. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
AndrĂŠ Amaral (3848752)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

First 25 exclusion categorisations for both investigators. This process was repeated for all 1155 ar...

Additional file 4: of From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

Maaike de Vries (3193380)
Diana van der Plaat (5926982)
Ivana Nedeljkovic (5118377)
Rikst Verkaik-Schakel (5926991)
Wierd Kooistra (151978)
Najaf Amin (114329)
Cornelia van Duijn (160701)
Corry-Anke Brandsma (41865)
Cleo van Diemen (3172971)
Judith Vonk (3569540)
H Marike Boezen (80129)

November 2018

Overview results of the association between DNA methylation and smoking status in lung tissue. (DOCX...

Additional file 5: of Genome-wide analysis of DNA methylation in bronchial washings

Sang-Won Um (535627)
Yujin Kim (483088)
Bo Lee (3463586)
Dongho Kim (29790)
Kyung-Jong Lee (5237399)
Hong Kim (101826)
Joungho Han (483091)
Hojoong Kim (535625)
Young Shim (3463580)
Duk-Hwan Kim (483093)

May 2018

Table S3. The correlation between pack-years of smoking and DNA methylation in 53 control groups. (D...

Additional file 1: Table S1. of Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection

Yun Su (289202)
HongBin Fang (3511388)
Feng Jiang (95012)

October 2016

Differential cell percentages of stage I non-small cell lung (NSCLC) patients and smokers with benig...

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Symen Ligthart (701678)
Carola Marzi (236979)
Stella Aslibekyan (123439)
Michael Mendelson (2697424)
Karen Conneely (3448694)
Toshiko Tanaka (174638)
Elena Colicino (3503048)
Lindsay Waite (3503021)
Roby Joehanes (560601)
Weihua Guan (345071)
Jennifer Brody (174723)
Cathy Elks (3503054)
Riccardo Marioni (669892)
Min Jhun (3503015)
Golareh Agha (3503030)
Jan Bressler (248795)
Cavin Ward-Caviness (3503057)
Brian Chen (149932)
Tianxiao Huan (599733)
Kelly Bakulski (3503063)
Elias Salfati (3503045)
Giovanni Fiorito (136942)
Simone Wahl (112749)
Katharina Schramm (528479)
Jin Sha (847984)
Dena Hernandez (215322)
Allan Just (3448679)
Jennifer Smith (172056)
Nona Sotoodehnia (143373)
Luke Pilling (3503024)
James Pankow (160621)
Phil Tsao (3503066)
Chunyu Liu (9855)
Wei Zhao (14321)
Simonetta Guarrera (136940)
Vasiliki Michopoulos (3503051)
Alicia Smith (3448658)
Marjolein Peters (3503033)
David Melzer (202058)
Pantel Vokonas (587472)
Myriam Fornage (45591)
Holger Prokisch (26590)
Joshua Bis (711982)
Audrey Chu (3503069)
Christian Herder (44905)
Harald Grallert (72666)
Chen Yao (137375)
Sonia Shah (142603)
Allan McRae (3400103)
Honghuang Lin (560598)
Steve Horvath (28847)
Daniele Fallin (3503039)
Albert Hofman (107303)
Nicholas Wareham (153226)
Kerri Wiggins (3503018)
Andrew Feinberg (242567)
John Starr (231855)
Peter Visscher (3400094)
Joanne Murabito (3503036)
Sharon Kardia (3503060)
Devin Absher (217357)
Elisabeth Binder (3448661)
Andrew Singleton (23294)
Stefania Bandinelli (150002)
Annette Peters (62601)
Melanie Waldenberger (236985)
Giuseppe Matullo (136983)
Joel Schwartz (18324)
Ellen Demerath (198657)
AndrĂŠ Uitterlinden (3404267)
Joyce van Meurs (3404240)
Oscar Franco (2885594)
Yii-Der Chen (3503075)
Daniel Levy (51573)
Stephen Turner (3503027)
Ian Deary (489588)
Kerry Ressler (3503072)
JosĂŠe Dupuis (3503084)
Luigi Ferrucci (150038)
Ken Ong (448067)
Themistocles Assimes (746456)
Eric Boerwinkle (36288)
Wolfgang Koenig (26222)
Donna Arnett (192289)
Andrea Baccarelli (36523)
Emelia Benjamin (3503042)
Abbas Dehghan (174878)

December 2016

Significant methylation-expression results and corresponding expression-CRP results for the replicat...

Additional file 8: Table S7. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.05). (C...

Additional file 7: Table S6. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to COPD vs. smokers (Pâ<â0.01). (CSV 19 k...

Additional file 5: Table S4. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.01). (C...

Additional file 2: Table S1. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to smokers vs. non-smokers (Pâ<â0.001). (...

Additional file 3: Table S2. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

CpGs differentially methylated in lung DNA in relation to COPD vs. non-smokers (Pâ<â0.001). (CSV...

Additional file 1: Figures S1-S13. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Isaac Sundar (3927785)
Qiangzong Yin (3927788)
Brian Baier (517434)
Li Yan (107001)
Witold Mazur (2118115)
Dongmei Li (176178)
Martha Susiarjo (23984)
Irfan Rahman (333928)

April 2017

Figure S1.Boxplot shows distribution of pre-processed DNA methylation level (Î˛ values) from all the...

Additional file 1: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Table S1. (.MWD): DNA regions differentially methylated with COPD status in airway fibroblasts. Summ...

Additional file 3: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Figure S1. (.EPS): CpG methylation variation in parenchymal fibroblasts in COPD samples. A) Plot of ...

Additional file 1: Tables S1. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
André Amaral (3848719)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

Search terms (n = 92) used within MEDLINE, EMBASE and Web of Science. (DOCX 13 kb

Additional file 4: of Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Rachel Clifford (4913317)
Nick Fishbane (517664)
Jamie Patel (4913314)
Julia MacIsaac (3575030)
Lisa McEwen (3968174)
Andrew Fisher (1673086)
Corry-Anke Brandsma (41865)
Parameswaran Nair (463763)
Michael Kobor (3470795)
Tillie-Louise Hackett (92016)
Alan Knox (456628)

March 2018

Figure S2. (.EPS): GRIK2 methylation and expression do not correlate with smoking pack-years or smok...

Additional file 2: Tables S2. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
AndrĂŠ Amaral (3848752)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

First 25 exclusion categorisations for both investigators. This process was repeated for all 1155 ar...

Additional file 4: of From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

Maaike de Vries (3193380)
Diana van der Plaat (5926982)
Ivana Nedeljkovic (5118377)
Rikst Verkaik-Schakel (5926991)
Wierd Kooistra (151978)
Najaf Amin (114329)
Cornelia van Duijn (160701)
Corry-Anke Brandsma (41865)
Cleo van Diemen (3172971)
Judith Vonk (3569540)
H Marike Boezen (80129)

November 2018

Overview results of the association between DNA methylation and smoking status in lung tissue. (DOCX...

Additional file 5: of Genome-wide analysis of DNA methylation in bronchial washings

Sang-Won Um (535627)
Yujin Kim (483088)
Bo Lee (3463586)
Dongho Kim (29790)
Kyung-Jong Lee (5237399)
Hong Kim (101826)
Joungho Han (483091)
Hojoong Kim (535625)
Young Shim (3463580)
Duk-Hwan Kim (483093)

May 2018

Table S3. The correlation between pack-years of smoking and DNA methylation in 53 control groups. (D...

Additional file 1: Table S1. of Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection

Yun Su (289202)
HongBin Fang (3511388)
Feng Jiang (95012)

October 2016

Differential cell percentages of stage I non-small cell lung (NSCLC) patients and smokers with benig...

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Symen Ligthart (701678)
Carola Marzi (236979)
Stella Aslibekyan (123439)
Michael Mendelson (2697424)
Karen Conneely (3448694)
Toshiko Tanaka (174638)
Elena Colicino (3503048)
Lindsay Waite (3503021)
Roby Joehanes (560601)
Weihua Guan (345071)
Jennifer Brody (174723)
Cathy Elks (3503054)
Riccardo Marioni (669892)
Min Jhun (3503015)
Golareh Agha (3503030)
Jan Bressler (248795)
Cavin Ward-Caviness (3503057)
Brian Chen (149932)
Tianxiao Huan (599733)
Kelly Bakulski (3503063)
Elias Salfati (3503045)
Giovanni Fiorito (136942)
Simone Wahl (112749)
Katharina Schramm (528479)
Jin Sha (847984)
Dena Hernandez (215322)
Allan Just (3448679)
Jennifer Smith (172056)
Nona Sotoodehnia (143373)
Luke Pilling (3503024)
James Pankow (160621)
Phil Tsao (3503066)
Chunyu Liu (9855)
Wei Zhao (14321)
Simonetta Guarrera (136940)
Vasiliki Michopoulos (3503051)
Alicia Smith (3448658)
Marjolein Peters (3503033)
David Melzer (202058)
Pantel Vokonas (587472)
Myriam Fornage (45591)
Holger Prokisch (26590)
Joshua Bis (711982)
Audrey Chu (3503069)
Christian Herder (44905)
Harald Grallert (72666)
Chen Yao (137375)
Sonia Shah (142603)
Allan McRae (3400103)
Honghuang Lin (560598)
Steve Horvath (28847)
Daniele Fallin (3503039)
Albert Hofman (107303)
Nicholas Wareham (153226)
Kerri Wiggins (3503018)
Andrew Feinberg (242567)
John Starr (231855)
Peter Visscher (3400094)
Joanne Murabito (3503036)
Sharon Kardia (3503060)
Devin Absher (217357)
Elisabeth Binder (3448661)
Andrew Singleton (23294)
Stefania Bandinelli (150002)
Annette Peters (62601)
Melanie Waldenberger (236985)
Giuseppe Matullo (136983)
Joel Schwartz (18324)
Ellen Demerath (198657)
AndrĂŠ Uitterlinden (3404267)
Joyce van Meurs (3404240)
Oscar Franco (2885594)
Yii-Der Chen (3503075)
Daniel Levy (51573)
Stephen Turner (3503027)
Ian Deary (489588)
Kerry Ressler (3503072)
JosĂŠe Dupuis (3503084)
Luigi Ferrucci (150038)
Ken Ong (448067)
Themistocles Assimes (746456)
Eric Boerwinkle (36288)
Wolfgang Koenig (26222)
Donna Arnett (192289)
Andrea Baccarelli (36523)
Emelia Benjamin (3503042)
Abbas Dehghan (174878)

December 2016

Significant methylation-expression results and corresponding expression-CRP results for the replicat...

Additional file 9: Table S8. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Abstract

Extracted data

Additional file 9: Table S8. of DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Abstract

Extracted data

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