Additional file 5: Figure S4. of Mechanisms of corticosteroid insensitivity in COPD alveolar macrophages exposed to NTHi

Signalling pathways of NTHi in COPD alveolar macrophage. COPD alveolar macrophages (n = 7) were stimulated with NTHi (10:1 MOI). Phosphorylation of NF-κB subunit (p65) (A) and p38 MAPK (B) was assessed at 0, 10, 20, 40 and 60 min of stimulation by Western blot analysis. Band density was normalized to β-Actin loading control. Representative blots are shown under matching conditions. Data presented as Mean ± SEM. *, **, *** represent significance above time matched basal controls (p < 0.05, 0.01, 0.001 respectively, Repeated measures ANOVA). (BMP 51738 kb