Early protection is not enhanced by circulating memory T cells.

<p>A) Naive, immune, and immune mice treated with FTY-720 or αCXCR3 were challenged intradermally in the ear with 2x10⁶ dsRed <i>L</i>. <i>major</i>. B) DTH response was monitored over the course of 3 days. C, D) Parasite burden (C) and the number of Ly6C⁺ monocytes in the infection site (D) was determined at 72 hrs. Data shown are from one experiment representative of two (n = 3 mice per group). E) Naive, immune, naive parabiotic, and immune parabiotic mice were challenged intradermally in the ear with 2x10⁶ dsRed <i>L</i>. <i>major</i>. F) DTH response was monitored over the course of 3 days. G, H) Parasite burden (G) and the number of Ly6C⁺ monocytes in the infection site (H) was determined at 72 hrs. Data shown are from one experiment representative of two (n = 3 mice per group). P < 0.05 = *; P < 0.01 = **; P < 0.001 = ***.