Effect of pre-treatment with V.D3 on CCl₄ toxicity, as assessed by Day-1 MDA levels, antioxidant power, hepatic ATP levels, and NADPH levels.

<p>Mice were treated as described in legend for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176524#pone.0176524.g002" target="_blank">Fig 2</a>. At 24 h after CCl₄ injection, animals were euthanized and livers were collected for determination of MDA levels (A), total antioxidant power (B), hepatic ATP levels (C), and hepatic NADPH levels (D). Data are presented as mean ± S.D. of 6 mice. * <i>P</i> < 0.05 and ** <i>P</i> < 0.01 versus control, ^# <i>P</i> < 0.05 and ^## <i>P</i> < 0.01 versus CCl₄ group.