Elite suppressor CD8 + T cell responses are not inhibited by ingenol-B.

<p>CD8 + T cells from 5ES were either not treated (NT) or pre-incubated with DMSO oringenol-B at 3 different doses for six hours, washed, then added to autologous CD4 + T cells infected with a lab strain HIV-1 pseudovirus at a 1:1 effector:target ratio. Percent suppression of viral replication was determined after 3 days. Triplicates were performed and mean values are shown for each individual.