TRPV2-KO mice present an improved cardiac function following an acute MI compared to WT.

<p>TRPV2-WT and TRPV2-KO animals that underwent an acute MI 5 days earlier were tested for monocyte/macrophage expression by staining with F4/80 antibody (A). Thirty days post MI their ejection fraction relative to baseline was determined by echocardiography (B). The scar size on day 30 was analyzed by Masson's trichrome staining- representative capture and bar graph demonstrating the mean scar size of all samples (C) and BNP expression relative to sham-operated control mice was determine by real-time PCR; AU- arbitrary units (D).