Ectopic expression of spermatogonia genes in <i>Kdm1a</i>^<i>Cagg</i> testes.

<p>DAPI (A,D), OCT4 (B,E), and combined (C,F) immunofluorescence from wild-type (A-C) and <i>Kdm1a</i>^<i>Cagg</i> testes (D-F). Arrowheads in (B) indicate spermatogonia marked by OCT4, whereas arrows in (E) indicate OCT4 protein in spermatocyte-like cells. Asterisk (E) indicates OCT4 protein in post-meiotic spermatid-like cells. Quantification of the OCT4 (G) ectopic protein phenotype (n = >50 tubules counted from multiple animals, Mann-Whitney U test, p < .001). Scale bars, 25 μm.