Correlations between clinical outcomes and metabolites/metabolite ratios in ALS.

Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

Bjornevik, Kjetil
Zhang, Zhongli
O\u27Reilly, Éilis J.
Berry, James D.
Clish, Clary B.
Deik, Amy
Jeanfavre, Sarah
Kato, Ikuko
Kelly, Rachel S.
Kolonel, Laurence N.
Liang, Liming
Le Marchand, Loic
McCullough, Marjorie L.
Paganoni, Sabrina
Pierce, Kerry A.
Schwarzschild, Michael A.
Shadyab, Aladdin H.
Wactawski-Wende, Jean
Wang, Dong D.
Wang, Ying

March 2019

Objective: To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic later...

Clinical correlations between the altered functional connectivity and the clinical rating scales.

Shin Teng (427228)
Chia-Feng Lu (427227)
Po-Shan Wang (300943)
Cheng-Ta Li (129522)
Pei-Chi Tu (129532)
Chih-I Hung (433720)
Tung-Ping Su (129556)
Yu-Te Wu (303371)

May 2014

Clinical correlations between the altered functional connectivity and the clinical rating scales....

Subcutaneous fat content correlates with disease progression of ALS patients.

Eva Lindauer (159115)
Luc Dupuis (159076)
Hans-Peter Müller (108329)
Heiko Neumann (106738)
Albert C. Ludolph (108339)
Jan Kassubek (67768)

June 2013

Correlations among total (FCMRI, A), subcutaneous (subFCMRI, B), visceral (...

Correlations between serum levels of metabolites and CP equivalent (mg) or duration of illness (months).

Takeshi Fukushima (594625)
Hideaki Iizuka (594626)
Ayaka Yokota (594627)
Takehiro Suzuki (299577)
Chihiro Ohno (594628)
Yumiko Kono (594629)
Minami Nishikiori (594630)
Ayaka Seki (594631)
Hideaki Ichiba (594632)
Yoshinori Watanabe (580483)
Seiji Hongo (399191)
Mamoru Utsunomiya (594633)
Masaki Nakatani (594634)
Kiyomi Sadamoto (594635)
Takashi Yoshio (594636)

July 2014

Correlations between serum levels of metabolites and CP equivalent (mg) or duration of illness (m...

Clinical statistics of the time frame of ALS-like symptoms with corresponding treatment doses.

Hasan Arrat (2211991)
Thomas J. Lukas (56752)
Teepu Siddique (326070)

May 2015

Clinical statistics of the time frame of ALS-like symptoms with corresponding treatment doses.</p

Pretreatment metabolites correlated with treatment outcomes in patients selected from the ends (comparing good and poor responders).

Rima Kaddurah-Daouk (152187)
Rebecca A. Baillie (152180)
Hongjie Zhu (152174)
Zhao-Bang Zeng (42537)
Michelle M. Wiest (342485)
Uyen Thao Nguyen (342486)
Katie Wojnoonski (342487)
Steven M. Watkins (242090)
Miles Trupp (152171)
Ronald M. Krauss (121420)

February 2013

Pretreatment metabolites correlated with treatment outcomes in patients selected from the ends (c...

Correlations between (a, left) ALSFRS-R bulbar subscore (/12) and articulatory rate (SPM); and (b, right) FVC (%) and Mean phrase durations (sec) with the coefficients of determination in patients with ALS.

Yana Yunusova (846862)
Naida L. Graham (846863)
Sanjana Shellikeri (846864)
Kent Phuong (846865)
Madhura Kulkarni (50844)
Elizabeth Rochon (846866)
David F. Tang-Wai (250450)
Tiffany W. Chow (846867)
Sandra E. Black (429293)
Lorne H. Zinman (846868)
Jordan R. Green (846869)

January 2016

Correlations between (a, left) ALSFRS-R bulbar subscore (/12) and articulatory rate (SPM); and (b...

A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression.

Hélène Blasco
Franck Patin
Amandine Descat
Guillaume Garçon
Philippe Corcia
Patrick Gelé
Timothée Lenglet
Peter Bede
Vincent Meininger
David Devos
Jean François Gossens
Pierre-François Pradat

January 2018

There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharma...

Correlations (Spearman r) between levels of individual analytes in CSF of ALS group, luminescence measured in arbitrary units in Shh-LTII assay and ALSFRS-R, disease duration, and disease progression rate.

Anna Drannik (3723370)
Joan Martin (3723373)
Randy Peterson (3723376)
Xiaoxing Ma (325109)
Fan Jiang (144211)
John Turnbull (342576)

February 2017

Correlations (Spearman r) between levels of individual analytes in CSF of ALS group, lumin...

A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression

Blasco, Hélène
Patin, Franck
Descat, Amandine
Garçon, Guillaume
Corcia, Philippe
Gelé, Patrick
Lenglet, Timothée
Bede, Peter
Meininger, Vincent
Devos, David
Gossens, Jean, François
Pradat, Pierre-François

January 2018

International audienceThere is an urgent and unmet need for accurate biomarkers in Amyotrophic Later...

Performance on ACCT subtests in ALS patients and healthy subjects. Data are expressed as Means (SD).

Barbara Poletti (753783)
Laura Carelli (2737702)
Andrea Faini (299439)
Federica Solca (753782)
Paolo Meriggi (2737708)
Annalisa Lafronza (753784)
Luciana Ciringione (5616812)
Elisa Pedroli (2737711)
Nicola Ticozzi (2737705)
Andrea Ciammola (209758)
Pietro Cipresso (306690)
Giuseppe Riva (33348)
Vincenzo Silani (181043)

August 2018

Performance on ACCT subtests in ALS patients and healthy subjects. Data are expressed as Means (S...

Concentrations of different metabolites in ALS (n = 50) and non ALS patients (n = 44).

Hélène Blasco (361150)
Philippe Corcia (136280)
Caroline Moreau (361151)
Ségolène Veau (361152)
Clémentine Fournier (361153)
Patrick Vourc'h (361154)
Patrick Emond (361155)
Paul Gordon (136278)
Pierre-François Pradat (360957)
Julien Praline (291109)
David Devos (361156)
Lydie Nadal-Desbarats (361157)
Christian R. Andres (361158)

February 2013

CSF concentrations of pyruvate (A), ascorbate (B), acetate (C) and acetone (D) are represented wi...

Absolute metabolic concentrations (mM in institutional units) and relative metabolic concentrations of the left motor cortex in ALS patients vs. age-matched healthy controls.

Nazem Atassi (3491174)
Maosheng Xu (429644)
Christina Triantafyllou (345013)
Boris Keil (2512966)
Robert Lawson (174820)
Paul Cernasov (4023110)
Elena Ratti (4023104)
Christopher J. Long (472050)
Sabrina Paganoni (4023113)
Alyssa Murphy (4023107)
Nouha Salibi (513865)
Ravi Seethamraju (4023116)
Bruce Rosen (632307)
Eva-Maria Ratai (353640)

May 2017

Absolute metabolic concentrations (mM in institutional units) and relative metabolic concentratio...

Metabolomics Biomarkers: A Strategy Toward Therapeutics Improvement in ALS

Lanznaster, Débora
de Assis, Denis Reis
Corcia, Philippe
Pradat, Pierre-François
Blasco, Hélène

December 2018

This is the accepted version of the following article: "Metabolomics Biomarkers: A Strategy Toward T...

Correlation among AA and LA parameters.

Edoardo Saccenti (217343)
John van Duynhoven (704663)
Doris M. Jacobs (704664)
Age K. Smilde (149094)
Huub C. J. Hoefsloot (175415)

March 2015

Heat-map for the correlation matrix among the parameters describing AA and LA downstream metaboli...

Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

Bjornevik, Kjetil
Zhang, Zhongli
O\u27Reilly, Éilis J.
Berry, James D.
Clish, Clary B.
Deik, Amy
Jeanfavre, Sarah
Kato, Ikuko
Kelly, Rachel S.
Kolonel, Laurence N.
Liang, Liming
Le Marchand, Loic
McCullough, Marjorie L.
Paganoni, Sabrina
Pierce, Kerry A.
Schwarzschild, Michael A.
Shadyab, Aladdin H.
Wactawski-Wende, Jean
Wang, Dong D.
Wang, Ying

March 2019

Objective: To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic later...

Clinical correlations between the altered functional connectivity and the clinical rating scales.

Shin Teng (427228)
Chia-Feng Lu (427227)
Po-Shan Wang (300943)
Cheng-Ta Li (129522)
Pei-Chi Tu (129532)
Chih-I Hung (433720)
Tung-Ping Su (129556)
Yu-Te Wu (303371)

May 2014

Clinical correlations between the altered functional connectivity and the clinical rating scales....

Subcutaneous fat content correlates with disease progression of ALS patients.

Eva Lindauer (159115)
Luc Dupuis (159076)
Hans-Peter Müller (108329)
Heiko Neumann (106738)
Albert C. Ludolph (108339)
Jan Kassubek (67768)

June 2013

Correlations among total (FCMRI, A), subcutaneous (subFCMRI, B), visceral (...

Correlations between serum levels of metabolites and CP equivalent (mg) or duration of illness (months).

Takeshi Fukushima (594625)
Hideaki Iizuka (594626)
Ayaka Yokota (594627)
Takehiro Suzuki (299577)
Chihiro Ohno (594628)
Yumiko Kono (594629)
Minami Nishikiori (594630)
Ayaka Seki (594631)
Hideaki Ichiba (594632)
Yoshinori Watanabe (580483)
Seiji Hongo (399191)
Mamoru Utsunomiya (594633)
Masaki Nakatani (594634)
Kiyomi Sadamoto (594635)
Takashi Yoshio (594636)

July 2014

Correlations between serum levels of metabolites and CP equivalent (mg) or duration of illness (m...

Clinical statistics of the time frame of ALS-like symptoms with corresponding treatment doses.

Hasan Arrat (2211991)
Thomas J. Lukas (56752)
Teepu Siddique (326070)

May 2015

Clinical statistics of the time frame of ALS-like symptoms with corresponding treatment doses.</p

Pretreatment metabolites correlated with treatment outcomes in patients selected from the ends (comparing good and poor responders).

Rima Kaddurah-Daouk (152187)
Rebecca A. Baillie (152180)
Hongjie Zhu (152174)
Zhao-Bang Zeng (42537)
Michelle M. Wiest (342485)
Uyen Thao Nguyen (342486)
Katie Wojnoonski (342487)
Steven M. Watkins (242090)
Miles Trupp (152171)
Ronald M. Krauss (121420)

February 2013

Pretreatment metabolites correlated with treatment outcomes in patients selected from the ends (c...

Correlations between (a, left) ALSFRS-R bulbar subscore (/12) and articulatory rate (SPM); and (b, right) FVC (%) and Mean phrase durations (sec) with the coefficients of determination in patients with ALS.

Yana Yunusova (846862)
Naida L. Graham (846863)
Sanjana Shellikeri (846864)
Kent Phuong (846865)
Madhura Kulkarni (50844)
Elizabeth Rochon (846866)
David F. Tang-Wai (250450)
Tiffany W. Chow (846867)
Sandra E. Black (429293)
Lorne H. Zinman (846868)
Jordan R. Green (846869)

January 2016

Correlations between (a, left) ALSFRS-R bulbar subscore (/12) and articulatory rate (SPM); and (b...

A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression.

Hélène Blasco
Franck Patin
Amandine Descat
Guillaume Garçon
Philippe Corcia
Patrick Gelé
Timothée Lenglet
Peter Bede
Vincent Meininger
David Devos
Jean François Gossens
Pierre-François Pradat

January 2018

There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharma...

Correlations (Spearman r) between levels of individual analytes in CSF of ALS group, luminescence measured in arbitrary units in Shh-LTII assay and ALSFRS-R, disease duration, and disease progression rate.

Anna Drannik (3723370)
Joan Martin (3723373)
Randy Peterson (3723376)
Xiaoxing Ma (325109)
Fan Jiang (144211)
John Turnbull (342576)

February 2017

Correlations (Spearman r) between levels of individual analytes in CSF of ALS group, lumin...

A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression

Blasco, Hélène
Patin, Franck
Descat, Amandine
Garçon, Guillaume
Corcia, Philippe
Gelé, Patrick
Lenglet, Timothée
Bede, Peter
Meininger, Vincent
Devos, David
Gossens, Jean, François
Pradat, Pierre-François

January 2018

International audienceThere is an urgent and unmet need for accurate biomarkers in Amyotrophic Later...

Performance on ACCT subtests in ALS patients and healthy subjects. Data are expressed as Means (SD).

Barbara Poletti (753783)
Laura Carelli (2737702)
Andrea Faini (299439)
Federica Solca (753782)
Paolo Meriggi (2737708)
Annalisa Lafronza (753784)
Luciana Ciringione (5616812)
Elisa Pedroli (2737711)
Nicola Ticozzi (2737705)
Andrea Ciammola (209758)
Pietro Cipresso (306690)
Giuseppe Riva (33348)
Vincenzo Silani (181043)

August 2018

Performance on ACCT subtests in ALS patients and healthy subjects. Data are expressed as Means (S...

Concentrations of different metabolites in ALS (n = 50) and non ALS patients (n = 44).

Hélène Blasco (361150)
Philippe Corcia (136280)
Caroline Moreau (361151)
Ségolène Veau (361152)
Clémentine Fournier (361153)
Patrick Vourc'h (361154)
Patrick Emond (361155)
Paul Gordon (136278)
Pierre-François Pradat (360957)
Julien Praline (291109)
David Devos (361156)
Lydie Nadal-Desbarats (361157)
Christian R. Andres (361158)

February 2013

CSF concentrations of pyruvate (A), ascorbate (B), acetate (C) and acetone (D) are represented wi...

Absolute metabolic concentrations (mM in institutional units) and relative metabolic concentrations of the left motor cortex in ALS patients vs. age-matched healthy controls.

Nazem Atassi (3491174)
Maosheng Xu (429644)
Christina Triantafyllou (345013)
Boris Keil (2512966)
Robert Lawson (174820)
Paul Cernasov (4023110)
Elena Ratti (4023104)
Christopher J. Long (472050)
Sabrina Paganoni (4023113)
Alyssa Murphy (4023107)
Nouha Salibi (513865)
Ravi Seethamraju (4023116)
Bruce Rosen (632307)
Eva-Maria Ratai (353640)

May 2017

Absolute metabolic concentrations (mM in institutional units) and relative metabolic concentratio...

Metabolomics Biomarkers: A Strategy Toward Therapeutics Improvement in ALS

Lanznaster, Débora
de Assis, Denis Reis
Corcia, Philippe
Pradat, Pierre-François
Blasco, Hélène

December 2018

This is the accepted version of the following article: "Metabolomics Biomarkers: A Strategy Toward T...

Correlation among AA and LA parameters.

Edoardo Saccenti (217343)
John van Duynhoven (704663)
Doris M. Jacobs (704664)
Age K. Smilde (149094)
Huub C. J. Hoefsloot (175415)

March 2015

Heat-map for the correlation matrix among the parameters describing AA and LA downstream metaboli...

Prediagnostic plasma metabolomics and the risk of amyotrophic lateral sclerosis

Bjornevik, Kjetil
Zhang, Zhongli
O\u27Reilly, Éilis J.
Berry, James D.
Clish, Clary B.
Deik, Amy
Jeanfavre, Sarah
Kato, Ikuko
Kelly, Rachel S.
Kolonel, Laurence N.
Liang, Liming
Le Marchand, Loic
McCullough, Marjorie L.
Paganoni, Sabrina
Pierce, Kerry A.
Schwarzschild, Michael A.
Shadyab, Aladdin H.
Wactawski-Wende, Jean
Wang, Dong D.
Wang, Ying

March 2019

Objective: To identify prediagnostic plasma metabolomic biomarkers associated with amyotrophic later...

Clinical correlations between the altered functional connectivity and the clinical rating scales.

Shin Teng (427228)
Chia-Feng Lu (427227)
Po-Shan Wang (300943)
Cheng-Ta Li (129522)
Pei-Chi Tu (129532)
Chih-I Hung (433720)
Tung-Ping Su (129556)
Yu-Te Wu (303371)

May 2014

Clinical correlations between the altered functional connectivity and the clinical rating scales....

Subcutaneous fat content correlates with disease progression of ALS patients.

Eva Lindauer (159115)
Luc Dupuis (159076)
Hans-Peter Müller (108329)
Heiko Neumann (106738)
Albert C. Ludolph (108339)
Jan Kassubek (67768)

June 2013

Correlations among total (FCMRI, A), subcutaneous (subFCMRI, B), visceral (...

Correlations between clinical outcomes and metabolites/metabolite ratios in ALS.

Abstract

Extracted data

Correlations between clinical outcomes and metabolites/metabolite ratios in ALS.

Abstract

Extracted data

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