PPh<sub>3</sub> Mediated Reductive Annulation Reaction between Isatins and Electron Deficient Dienes to Construct Spirooxindole Compounds

Lei Zhang (38117)
Hong Lu (58784)
Guo-Qiang Xu (3685465)
Zhu-Yin Wang (1566079)
Peng-Fei Xu (38571)

Publication date

May 2017

DOI

10.1021/acs.joc.7b00595.s001

Abstract

A PPh<sub>3</sub> mediated reductive annulation reaction between isatins and 4,4-dicyano-2-methylenebut-3-enoates was developed. The reaction provided an alternative method for constructing five- and three-membered all-carbon spirooxindole compounds. Lithium chloride as a Lewis acid played a key role in the synthesis of spirocyclopentenyl oxindole compounds

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PPh<sub>3</sub> Mediated Reductive Annulation Reaction between Isatins and Electron Deficient Dienes to Construct Spirooxindole Compounds

Abstract

Extracted data

PPh<sub>3</sub> Mediated Reductive Annulation Reaction between Isatins and Electron Deficient Dienes to Construct Spirooxindole Compounds

Abstract

Extracted data

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