<p>Plots showing the counts of <i>cis</i>- and <i>trans</i>-eQTL versus a range of FDR significance thresholds for each of the methods applied to every dataset.</p
<p>The numbers of the significant SNP-phenotype associations at various levels of false discovery ra...
Different percentages (P) of simulated DA features are on rows, while different sample size (SS) val...
<div><p>(A) For each major eQTL detected in LV, fat, kidney, and adrenal tissue, the expected FDR wa...
<p>The cutoff values for each FDR were determined via permutation; see <a href="http://www.plosgenet...
<p>FDR 0.05 level corresponds to <i>P</i>–value thresholds 4.8e-4 (<i>cis</i>) and 6.2e-10 (<i>trans...
<p>The numbers are based on the statistical procedure and threshold used in the original publication...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Numbers of significant eQTL with shown separately for cis-eQTL (left) and trans-eQTL (right). St...
<p>FDR: false discovery rate; FWER: family-wise error rate; SD: standard deviation; IQR: inter-quart...
<p>In each panel, for each <i>q</i>-value threshold, observed empirical FDRs are computed (by ClanOv...
<p>The False Discovery Rate (FDR) method for multiple comparisons utilises a variable criterion rang...
1<p>The <i>trans</i>-eQTL signals presented are probe-level signals.</p>2<p>r<sup>2</sup> is a measu...
<p>FDR, estimated by the average proportion of erroneously identified epistatic effects among all id...
<p>A) Diagram plotting the number of peptides (left) and PSMs (right) identified with each database ...
<p>(<b>a,b</b>) number of recovered <i>cis</i> and <i>trans</i> associations as a function of the ch...
<p>The numbers of the significant SNP-phenotype associations at various levels of false discovery ra...
Different percentages (P) of simulated DA features are on rows, while different sample size (SS) val...
<div><p>(A) For each major eQTL detected in LV, fat, kidney, and adrenal tissue, the expected FDR wa...
<p>The cutoff values for each FDR were determined via permutation; see <a href="http://www.plosgenet...
<p>FDR 0.05 level corresponds to <i>P</i>–value thresholds 4.8e-4 (<i>cis</i>) and 6.2e-10 (<i>trans...
<p>The numbers are based on the statistical procedure and threshold used in the original publication...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Numbers of significant eQTL with shown separately for cis-eQTL (left) and trans-eQTL (right). St...
<p>FDR: false discovery rate; FWER: family-wise error rate; SD: standard deviation; IQR: inter-quart...
<p>In each panel, for each <i>q</i>-value threshold, observed empirical FDRs are computed (by ClanOv...
<p>The False Discovery Rate (FDR) method for multiple comparisons utilises a variable criterion rang...
1<p>The <i>trans</i>-eQTL signals presented are probe-level signals.</p>2<p>r<sup>2</sup> is a measu...
<p>FDR, estimated by the average proportion of erroneously identified epistatic effects among all id...
<p>A) Diagram plotting the number of peptides (left) and PSMs (right) identified with each database ...
<p>(<b>a,b</b>) number of recovered <i>cis</i> and <i>trans</i> associations as a function of the ch...
<p>The numbers of the significant SNP-phenotype associations at various levels of false discovery ra...
Different percentages (P) of simulated DA features are on rows, while different sample size (SS) val...
<div><p>(A) For each major eQTL detected in LV, fat, kidney, and adrenal tissue, the expected FDR wa...
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