Additional file 3: of Insights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto

Amino acid alignment of bat (Ptal) MHC-II B genes, (A) DMB, (B) DOB, (C) DPB, (D) DQB and (E) DRB, against various vertebrates. Dashes indicate identical residues; Dots indicate gaps; P Peptide-Binding Sites; 4 CD4 Interaction Sites; C Cysteine residues in β1 and β2 domains likely to form intra-chain disulphide bonds. Percentage similarity of sequences within a particular β domain is reflected at the end of their respective sequences, with reference to the top sequence in the alignment. Red and blue represent percentage similarity of nucleotides and amino acid residues respectively within the stated β1 and β2 domains. Hosa – Homo sapiens; Eqca – Equus caballus; Susc – Sus scrofa; Mumu – Mus musculus; Ovar – Ovis aries; Orcu – Oryctolagus cuniculus; Gaga – Gallus gallus. (DOC 364 kb