Effects of Brusatol on mouse oocyte maturation.

<p>A) Quantitative analysis of GVBD and Pb1 extrusion in different treatment groups (control, 20 nM, 50 nM, 100 nM, 200 nM and 1000 nM). B) Polar body extrusion failure after Brusatol treated. Images were acquired with a camera on a stereomicroscope. Arrows showed that the control oocytes extruded the polar body while the treated oocytes failed. Scale bar, 100 μm. *p < 0.05 vs controls.