Apoptosis induced by TNFα antagonists in mTNF-transfected Jurkat T cells.

<p>(A) mTNF-transfected Jurkat T cells were untreated or treated with TNFα antagonists or rituximab, at 100 nM and cultured for 24 hours. The stimulated cells were stained with FITC-conjugated Annexin V and PI and were then analyzed by flow cytometry. Ten thousand cells were measured and plotted. The proportion of cells residing in each quadrant is expressed as a percentage. (B) The proportions of Annexin V-positive cells in each sample after stimulation are indicated as solid columns.