cGAS is not required for canonical inflammasome responses to <i>C</i>. <i>trachomatis</i> infection.
- Steve J. Webster (4060771)
- Sven Brode (4060789)
- Lou Ellis (4060786)
- Timothy J. Fitzmaurice (446008)
- Matthew J. Elder (4060774)
- Nelson O. Gekara (250192)
- Panagiotis Tourlomousis (694168)
- Clare Bryant (694171)
- Simon Clare (125268)
- Ronnie Chee (4060783)
- Hill J. S. Gaston (4060780)
- Jane C. Goodall (4060777)
Publication date
June 2017
DOIAbstract
<p>(A) IL-1β release measured by ELISA or (B) cell death measured by LDH release in supernatants from wild-type (cGAS<sup>+/+</sup>) or cGAS deficient (cGAS<sup>-/-</sup>) BMDM infected with <i>C</i>. <i>trachomatis</i> (CT) for 24hrs. Data represent the mean from BMDM obtained from three individual mice, error bars indicate ±SEM **p = <0.01, ***p = <0.001.</p
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