Additional file 2: Figure S2. Expression of SIRT1 in different regions of DLB and control brain tissue. The levels of SIRT1 were determined in different regions of DLB patients and were compared to a control-cohort. SIRT1 band intensity was normalised with GAPDH. Data are presented as fold change (±SD) with respect to control from three independent replicates with comparison to GAPDH as a housekeeping control protein. **p < 0.01 and *p < 0.05 when compared to control, t test. Images are representative blots of SIRT1 and GAPDH. M denotes molecular weight marker lane
Abstract Multiple sclerosis (MS) is a demyelinating disease characterized by chronic inflammation of...
<p>Representative Drp1 blots are shown with the corresponding β-actin blot using standard western bl...
<p>Sirtuin enzymes are a family of highly seven conserved protein deacetylases, namely SIRT1 through...
Abstract Background Sirtuins (SIRTs) are NAD+ dependent lysine deacetylases which are conserved from...
Background Dopamine (DA) neuron-selective uptake and toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydr...
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the degeneration of dopami...
Additional file 2: Table S1. Brain regions with gray matter volume reduction in the patients with Pa...
Tese de mestrado, Biologia molecular e humana, 2008, Universidade de Lisboa, Faculdade de CiênciasRe...
International audienceWe performed transcriptome analysis using RNA sequencing on substantia nigra p...
α-Synuclein is a key molecule in the pathogenesis of synucleinopathy including dementia with Lewy bo...
Sirtuin 2 (SIRT2) is thought to be important in the pathogenesis of Parkinson’s disease (PD), and th...
Nuclear receptor related 1 protein (NURR1), a transcription factor as key player for maintaining dop...
The NAD+-dependent deacetylase protein Sirtuin 3 (SIRT3) is emerging among the factors playing a key...
Mitochondrial dysfunction plays a major role in the progressive and pathological development of Park...
Additional file 5: Figure S2. Genetics and mitochondrial protein synthesis. Results are represented ...
Abstract Multiple sclerosis (MS) is a demyelinating disease characterized by chronic inflammation of...
<p>Representative Drp1 blots are shown with the corresponding β-actin blot using standard western bl...
<p>Sirtuin enzymes are a family of highly seven conserved protein deacetylases, namely SIRT1 through...
Abstract Background Sirtuins (SIRTs) are NAD+ dependent lysine deacetylases which are conserved from...
Background Dopamine (DA) neuron-selective uptake and toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydr...
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the degeneration of dopami...
Additional file 2: Table S1. Brain regions with gray matter volume reduction in the patients with Pa...
Tese de mestrado, Biologia molecular e humana, 2008, Universidade de Lisboa, Faculdade de CiênciasRe...
International audienceWe performed transcriptome analysis using RNA sequencing on substantia nigra p...
α-Synuclein is a key molecule in the pathogenesis of synucleinopathy including dementia with Lewy bo...
Sirtuin 2 (SIRT2) is thought to be important in the pathogenesis of Parkinson’s disease (PD), and th...
Nuclear receptor related 1 protein (NURR1), a transcription factor as key player for maintaining dop...
The NAD+-dependent deacetylase protein Sirtuin 3 (SIRT3) is emerging among the factors playing a key...
Mitochondrial dysfunction plays a major role in the progressive and pathological development of Park...
Additional file 5: Figure S2. Genetics and mitochondrial protein synthesis. Results are represented ...
Abstract Multiple sclerosis (MS) is a demyelinating disease characterized by chronic inflammation of...
<p>Representative Drp1 blots are shown with the corresponding β-actin blot using standard western bl...
<p>Sirtuin enzymes are a family of highly seven conserved protein deacetylases, namely SIRT1 through...