<p>Representative images of mice of different ages, 80 days mice (n = 6), 6 months mice (n = 6), 18 months mice (n = 6), 24 months mice (n = 3) (A). HE staining of the skin from different ages mice (B,C), For HE and Masson staining, representative images from 8–16 tissue sections in 2–6 mice are shown the thickness of full skin and epidermis of different age mice(D,E).Data are expressed as the mean ± s.e.m. *** P<0.005, unpaired t-test, two-tailed. Scale bars, 50 μm.</p
(A) Whole-mount tail epidermis stained with K10 (differentiation marker of interscale, red), K31 (di...
<p><b>A:</b> Notch1 is expressed in all layers of the adult skin whereas Notch2 is expressed only in...
<p>(a) Gross inspection. 7.5 month WMΔ mice could be identified by touch. Skin felt thicker and was ...
<p>Representative results of Western blotting analysis of skin tissues from mice aged 80 days, 6 mon...
Previous studies suggest that Akt signaling promotes tissue regeneration and decreased Akt activitie...
(A) Schematic diagram of the mouse tail skin. (B) Hematoxylin-eosin stained tail skin sections of yo...
<p>All analyses performed between 20–22 weeks of age; number of mice studied: 7–20 per group.</p><p>...
<p>A) Bhd<sup>f/f</sup> K14-cre mice exhibit acanthosis and hyperkeratosis (arrows) compared to litt...
(A) Schematic view of the interscale and scale IFE differentiation in the tail whole-mount epidermis...
<p>(<b>A</b>) Body weight of wild-type and <i>Akt1</i><sup>+/–</sup> female mice at 14 weeks and 40 ...
<p>(Upper panel). Representative histological sections of skin after incisional cutaneous wounds in ...
<p>(A) H&E staining (upper panel), Masson's trichrome staining (lower panel) of 1-year-old WT, HT, a...
<p>(A) Pictures of mice at 7 month-old and 10 month-old showing their coat phenotype (n = 6/group). ...
<p>(A) Images show skin sections from 12–16 wk old mice of the indicated strain stained with H&E and...
(A, B) Tail whole-mount epidermal sheets are stained with cleaved caspase-3 (apoptosis marker, red),...
(A) Whole-mount tail epidermis stained with K10 (differentiation marker of interscale, red), K31 (di...
<p><b>A:</b> Notch1 is expressed in all layers of the adult skin whereas Notch2 is expressed only in...
<p>(a) Gross inspection. 7.5 month WMΔ mice could be identified by touch. Skin felt thicker and was ...
<p>Representative results of Western blotting analysis of skin tissues from mice aged 80 days, 6 mon...
Previous studies suggest that Akt signaling promotes tissue regeneration and decreased Akt activitie...
(A) Schematic diagram of the mouse tail skin. (B) Hematoxylin-eosin stained tail skin sections of yo...
<p>All analyses performed between 20–22 weeks of age; number of mice studied: 7–20 per group.</p><p>...
<p>A) Bhd<sup>f/f</sup> K14-cre mice exhibit acanthosis and hyperkeratosis (arrows) compared to litt...
(A) Schematic view of the interscale and scale IFE differentiation in the tail whole-mount epidermis...
<p>(<b>A</b>) Body weight of wild-type and <i>Akt1</i><sup>+/–</sup> female mice at 14 weeks and 40 ...
<p>(Upper panel). Representative histological sections of skin after incisional cutaneous wounds in ...
<p>(A) H&E staining (upper panel), Masson's trichrome staining (lower panel) of 1-year-old WT, HT, a...
<p>(A) Pictures of mice at 7 month-old and 10 month-old showing their coat phenotype (n = 6/group). ...
<p>(A) Images show skin sections from 12–16 wk old mice of the indicated strain stained with H&E and...
(A, B) Tail whole-mount epidermal sheets are stained with cleaved caspase-3 (apoptosis marker, red),...
(A) Whole-mount tail epidermis stained with K10 (differentiation marker of interscale, red), K31 (di...
<p><b>A:</b> Notch1 is expressed in all layers of the adult skin whereas Notch2 is expressed only in...
<p>(a) Gross inspection. 7.5 month WMΔ mice could be identified by touch. Skin felt thicker and was ...