MSC promote the accumulation of DC and the activation of DC and macrophages in the lungs of uninfected mice.

<p>Uninfected mice and mice challenged with <i>Mtb</i> (600 CFU/mouse given aerogenically) were transferred with MSC as described in the legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0178983#pone.0178983.g002" target="_blank">Fig 2</a> and lung cell suspensions were analyzed by flow cytometry. A, Identification of CD11c⁺F4/80^- (DC) and CD11c^-F4/80⁺ (macrophages) populations by flow cytometry. B, Representative example showing the expression of IA/IE and CD11b by lung DC. C, E, Summarized data showing percentages of DC (C) and macrophages (E). D, F, Summarized data showing the expression of MHC class II by DC (D) and macrophages (F).