Neural progenitor cell proliferation in the hypothalamus is involved in acquired heat tolerance in long-term heat-acclimated rats - Fig 3

<p>(A) BrdU/c-Fos immunostaining. Arrows denote BrdU/c-Fos immune positive (BrdU+/c-Fos+) cells in the hypothalamus. 3V; third ventricle. Bar; 100 μm. Right panels show magnified views of boxed regions from LTHA rats. (B) The percentage of BrdU+/c-Fos+ cells in the hypothalamus was significantly increased with 40-day heat exposure. Values are the means ± SEM (n = 4 in each group). ** significant difference between LTCN and LTHA groups (p < 0.001).