CLSM images and graphics showing the immunoreactivity for NK₁R, SP, and CGRP in T13 DRG cells.

<p>The images show small (S), intermediate (I) and large (L) neurons surrounded by satellite cells. The receptor and neurokinins are present in both nuclear and cytosolic compartments. NK₁R immunoreactivity was enhanced in LP (B) compared with NP (A) as shown by the histogram of quantification (C). Conversely, SP and CGRP expression was reduced in LP (E and H, respectively) compared with NP (D and G) rats. The statistical significance can be viewed in F and I. The data are reported as the means ± scatter dot plot; n = 15 animals for each group; *P ≤ 0.05 vs. NP offspring (Student’s t-test).