Related to Fig. 1. Mov10 levels are elevated in Friend virus B-type (FVB) mice and are independent of sex. A) FVB brain (25 μg) at ages indicated, immunoblotted for Mov10 and eIF5α (loading control). Quantification of three independent experiments. Error bars represent SD, and p value indicates **p < 0.01 compared to adult. B) Top panel: 25 μg of P0 brains from 2 male and 2 female mice were immunoblotted for Mov10. 25 μg of adult brain lysate was used for comparison. Bottom panel: Genomic DNA was isolated from the P2 brain lysates of each mouse, and PCR was performed using SRY primers. Actin was used as a PCR control. (PDF 307 kb
Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...
Brain levels of the β-site of APP cleaving enzyme (BACE-1) mRNA. Expression levels of mRNA were norm...
Figure S2. Effects of maternal VAC and MIA on neurons and BDNF in the cerebral cortex of animals at ...
Related to Fig. 1. Mov10 is nuclear in P0 cortex and hippocampal cultures compared to adult. A) DAB ...
Figure S1. Comparison of mono-synaptic labeling between rAAV2-retro and RV-∆G under Cre expression i...
Figures S1 through S10. Figure S1. Transcript expression of Tmem106b in Tmem106b deficiency mice at ...
Adult (6–8 weeks old) and aged (16–18 weeks old) male BALB/c mice were provided diets formulated wit...
Figure S6. Validation of Knockdown Efficiency of shRNAs and Inhibitory Effect of CREST on Transcript...
Figure S1. AAV infect astrocytes selectively. To validate astrocyte tropism of the AAVs used in our ...
Figure S1. Analysis of APP levels in uninoculated AppNL-F mice. a Immunoblots of brain homogenates f...
Figure S3. The expressions of BiP and CHOP in the brains of the APP/PS1 transgenic mice and age- and...
AQP4 deficiency increased reactive astrogliosis and Aβ plaque deposits in 6.5 month-old APP/PS1 mice...
PLX5622 broadly depletes Iba1+ cells. Mice were fed chow containing PLX5622 or control chow for 2 we...
Figure S1. MOV10 antibody validation. Figure S2. The purity of isolated cell populations. Figure S3....
PLX5622 treatment does not enhance BBB permeability. Mice were fed PLX5622 chow or control chow for ...
Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...
Brain levels of the β-site of APP cleaving enzyme (BACE-1) mRNA. Expression levels of mRNA were norm...
Figure S2. Effects of maternal VAC and MIA on neurons and BDNF in the cerebral cortex of animals at ...
Related to Fig. 1. Mov10 is nuclear in P0 cortex and hippocampal cultures compared to adult. A) DAB ...
Figure S1. Comparison of mono-synaptic labeling between rAAV2-retro and RV-∆G under Cre expression i...
Figures S1 through S10. Figure S1. Transcript expression of Tmem106b in Tmem106b deficiency mice at ...
Adult (6–8 weeks old) and aged (16–18 weeks old) male BALB/c mice were provided diets formulated wit...
Figure S6. Validation of Knockdown Efficiency of shRNAs and Inhibitory Effect of CREST on Transcript...
Figure S1. AAV infect astrocytes selectively. To validate astrocyte tropism of the AAVs used in our ...
Figure S1. Analysis of APP levels in uninoculated AppNL-F mice. a Immunoblots of brain homogenates f...
Figure S3. The expressions of BiP and CHOP in the brains of the APP/PS1 transgenic mice and age- and...
AQP4 deficiency increased reactive astrogliosis and Aβ plaque deposits in 6.5 month-old APP/PS1 mice...
PLX5622 broadly depletes Iba1+ cells. Mice were fed chow containing PLX5622 or control chow for 2 we...
Figure S1. MOV10 antibody validation. Figure S2. The purity of isolated cell populations. Figure S3....
PLX5622 treatment does not enhance BBB permeability. Mice were fed PLX5622 chow or control chow for ...
Lentiviral-mediated overexpression of the Green Fluorescent Protein (GFP) in the mouse cerebellum. F...
Brain levels of the β-site of APP cleaving enzyme (BACE-1) mRNA. Expression levels of mRNA were norm...
Figure S2. Effects of maternal VAC and MIA on neurons and BDNF in the cerebral cortex of animals at ...