<p>(A) Blue and pink lines show the viral load relative to baseline for study participants in the QUAD treatment and RAL-combination therapy, respectively. Black lines represent the median values for each group. In the last phase, between about day 15 and day 30, the viral load in the RAL-combination participants is ~1-log lower (Δ~90% reduction) than the viral load in the quad-therapy group participants. (B) The median viral load profiles for each group present two phases of decay (1a and 2), but in addition the RAL-combination therapy includes an intermediate phase, 1b.</p
<p>Plasma viral RNA load was determined by real time RT-PCR. Boxed areas (ART) indicate period of an...
<p>RAL = lopinavir/ritonavir+raltegravir Control = lopinavir/ritonavir+2/3 nucleoside/nucleotide rev...
Objective: Model trajectories of viral load measurements from time of starting combination antiretro...
<p>Panel A: Correlation between the area under the viral load curve at peak (AUC) following viral re...
A. Example of viral load trajectories for animals treated on days 4 (blue), 6 (green), 27 (red) from...
<p>A) After drug treatment, the viral load declines proportionally to the number of virus-producing ...
Objectives and design: The dynamics of viral decline following the initiation of antiretroviral trea...
The impact of viral load (VL) decay and cumulative VL on CD4 recovery and AIDS after highly-active a...
<p>Panel A: Pre and post therapy <i>Log<sub>10</sub></i> viral load set points of four SIVmac251 inf...
<p>Panel A: Comparison (two tailed <i>t</i>-test) of the antiretroviral efficacy of H-iART and iART....
<p>Arrows with numbers below X-axis indicate time of initiation of antiretroviral therapy with RT in...
<p>(A) Calculation of the set-point viral load and CD4+ T-cell decline, illustrated for a single ind...
The kinetics of HIV-1 decay under treatment depends on the class of antiretrovirals used. Mathematic...
<p>Top panel shows Kaplan-Meyer plot summarizing time to a viral load of more than 5,000 copies/ml i...
<div><p>(A) Dynamics in the absence of therapy.</p><p>(B) Decline in viral load during potent triple...
<p>Plasma viral RNA load was determined by real time RT-PCR. Boxed areas (ART) indicate period of an...
<p>RAL = lopinavir/ritonavir+raltegravir Control = lopinavir/ritonavir+2/3 nucleoside/nucleotide rev...
Objective: Model trajectories of viral load measurements from time of starting combination antiretro...
<p>Panel A: Correlation between the area under the viral load curve at peak (AUC) following viral re...
A. Example of viral load trajectories for animals treated on days 4 (blue), 6 (green), 27 (red) from...
<p>A) After drug treatment, the viral load declines proportionally to the number of virus-producing ...
Objectives and design: The dynamics of viral decline following the initiation of antiretroviral trea...
The impact of viral load (VL) decay and cumulative VL on CD4 recovery and AIDS after highly-active a...
<p>Panel A: Pre and post therapy <i>Log<sub>10</sub></i> viral load set points of four SIVmac251 inf...
<p>Panel A: Comparison (two tailed <i>t</i>-test) of the antiretroviral efficacy of H-iART and iART....
<p>Arrows with numbers below X-axis indicate time of initiation of antiretroviral therapy with RT in...
<p>(A) Calculation of the set-point viral load and CD4+ T-cell decline, illustrated for a single ind...
The kinetics of HIV-1 decay under treatment depends on the class of antiretrovirals used. Mathematic...
<p>Top panel shows Kaplan-Meyer plot summarizing time to a viral load of more than 5,000 copies/ml i...
<div><p>(A) Dynamics in the absence of therapy.</p><p>(B) Decline in viral load during potent triple...
<p>Plasma viral RNA load was determined by real time RT-PCR. Boxed areas (ART) indicate period of an...
<p>RAL = lopinavir/ritonavir+raltegravir Control = lopinavir/ritonavir+2/3 nucleoside/nucleotide rev...
Objective: Model trajectories of viral load measurements from time of starting combination antiretro...