Cannabinoids disrupt memory encoding by functionally isolating hippocampal CA1 from CA3 - Fig 3

<p>Average feedforward (A) and feedback (B) filter spectra in control and THC sessions (top), and their differences (bottom). Same format and analysis as <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005624#pcbi.1005624.g001" target="_blank">Fig 1a</a>. (C) Correlation between feedforward filter excitatory index (EI) reduction and behavioral deficits. Each point represents a specific THC session, with points of the same color coming from the same animal. X-axis shows reduction in feedforward EI, while y-axis shows reduction in behavioral performance. Both reductions were taken relative to control sessions (see supplemental methods). (D) Same as (C) but for feedback EI <i>increase</i>.