Effect of IL-10 in macrophages during <i>B</i>. <i>pseudomallei</i> infection.

<p>(A) Quantitative real-time PCR analysis of IL-10 expression in macrophages from C57BL/6 WT and <i>caspase6</i>^<i>-/-</i> mice 6 h after infection with <i>B</i>. <i>pseudomallei</i> strain E8 (MOI ~ 50). The data were logarithmized to achieve normal distribution and compared using Student’s <i>t</i>-test. Values are means ± standard deviations from three independent experiments. (B) Intracellular bacterial burden of IL-10-treated and non-treated C57BL/6 macrophages after infection with <i>B</i>. <i>pseudomallei</i> strain E8 (MOI ~ 25). Data were analysed using Student’s <i>t</i>-test. Values are means ± standard deviations from triplicate determinations. The experiment was repeated three times.