<p>Quantitative real-time PCR analysis of inflammatory parameters in the spleens of C57BL/6 WT and <i>caspase6</i><sup><i>-/-</i></sup> mice. Mice were infected with 5 × 10<sup>4</sup> CFU of <i>B</i>. <i>pseudomallei</i> strain E8 i.v. for 24 h. Uninfected control animals received PBS. Each of the 4 groups contained 9 mice from 3 replicates (n = 36). Data were analysed using Student’s <i>t</i> test. Values are means ± standard deviations from three independent experiments.</p
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
<p>The levels of IL-6 and TNF-α were determined from lavage fluids collected from the lungs of TLR2<...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
<p>Quantitative real-time PCR analysis of inflammatory parameters in the spleens of C57BL/6 WT (n = ...
<p>BALB/c mice were intranasally infected with <i>B. pseudomallei</i> E8 wild-type and ΔBsaK at 40 C...
<p>(A) Quantitative real-time PCR analysis of IL-10 expression in macrophages from C57BL/6 WT and <i...
<div><p>Caspase-6 is a member of the executioner caspases and known to play a role in innate and ada...
BALB/c (A) and C57BL/6 mice (B) were exposed to B. pseudomallei 1106a. In most cases N = 5.</p
<p>(A) Mice were infected intranasaly with <i>B</i>. <i>thailandensis</i> (10<sup>5</sup> CFU) and t...
<p>Intracellular bacterial burden of C57BL/6-WT and C57BL/6-<i>caspase6</i><sup><i>-/-</i></sup> mac...
Melioidosis is a potentially fatal disease of both human and animals caused by the bacterium Burkhol...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<p>Pulmonary cytokine concentrations after intranasal infection with 2.5×10<sup>2</sup> CFU <i>B. ps...
<p>Pulmonary and plasma cytokine levels after intranasal infection with 750 CFU of <i>B. pseudomalle...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
<p>The levels of IL-6 and TNF-α were determined from lavage fluids collected from the lungs of TLR2<...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
<p>Quantitative real-time PCR analysis of inflammatory parameters in the spleens of C57BL/6 WT (n = ...
<p>BALB/c mice were intranasally infected with <i>B. pseudomallei</i> E8 wild-type and ΔBsaK at 40 C...
<p>(A) Quantitative real-time PCR analysis of IL-10 expression in macrophages from C57BL/6 WT and <i...
<div><p>Caspase-6 is a member of the executioner caspases and known to play a role in innate and ada...
BALB/c (A) and C57BL/6 mice (B) were exposed to B. pseudomallei 1106a. In most cases N = 5.</p
<p>(A) Mice were infected intranasaly with <i>B</i>. <i>thailandensis</i> (10<sup>5</sup> CFU) and t...
<p>Intracellular bacterial burden of C57BL/6-WT and C57BL/6-<i>caspase6</i><sup><i>-/-</i></sup> mac...
Melioidosis is a potentially fatal disease of both human and animals caused by the bacterium Burkhol...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<p>Pulmonary cytokine concentrations after intranasal infection with 2.5×10<sup>2</sup> CFU <i>B. ps...
<p>Pulmonary and plasma cytokine levels after intranasal infection with 750 CFU of <i>B. pseudomalle...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
<p>The levels of IL-6 and TNF-α were determined from lavage fluids collected from the lungs of TLR2<...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...