Adipose-specific <i>Gpr43</i> transgenic mice (<i>aP2-Gpr43TG</i> mice) are lean and enhance insulin sensitivity.

<p>Body weights (a), tissue weights (b), and macroscopic appearance (c) of control WT and <i>aP2-Gpr43TG</i> mice fed an NC (n = 6−8). Scale bar: 10 mm. GTT (d) and ITT (e) in control WT and <i>aP2-Gpr43TG</i> mice fed an NC (n = 6−8). Mice were analyzed at 16 weeks of age. All data are presented as mean ± S.E.M. *<i>p</i> < 0.05, **<i>p</i> < 0.01, N.S.: not significant. epi: epididymal adipose tissue, peri: perirenal adipose tissue, sub: subcutaneous adipose tissue.