Meta-regression plot and forest plot of treatment success rates and mean age.

<p><b>Fig 5A Meta-regression plot correction of mean age and treatment success rate</b>. From the meta-regression plot correction, we determined that younger age correlated with higher efficacy. The point of determination for difference in efficacy is about 45 years old. <b>Fig 5B Treatment success rate from subgroup analysis of mean age, with patients younger and older than 45 years</b>.