<div><p>Huntington’s Disease (HD) is an autosomal dominant progressive neurodegenerative disorder characterized by cognitive, behavioral and motor dysfunctions. HD is caused by a CAG repeat expansion in exon 1 of the HD gene that is translated into an expanded polyglutamine tract in the encoded protein, huntingtin (HTT). While the most significant neuropathology of HD occurs in the striatum, other brain regions are also affected and play an important role in HD pathology. To date there is no cure for HD, and recently strategies aiming at silencing HTT expression have been initiated as possible therapeutics for HD. However, the essential functions of HTT in the adult brain are currently unknown and hence the consequence of sustained suppress...
Huntington’s disease (HD) is a genetic neurodegenerative disorder caused by expansion of a CAG repea...
Huntington’s disease (HD) is the most common dominantly-inherited neurodegenerative disease and affe...
Huntington disease (HD) results from polyglutamine expansion in the huntingtin protein (htt). Despit...
Huntington's disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and p...
<div><p>Huntington’s disease (HD) is a fatal neurodegenerative disease, characterized by motor defec...
Huntington’s Disease is an adult-onset dominant heritable disorder characterized by progressive psyc...
BackgroundHuntington's disease (HD) is a progressive neurodegenerative disorder associated with agin...
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation i...
Huntington’s disease (HD) is caused by the expansion of a CAG repeat in the huntingtin (HTT) gene. T...
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuro...
Huntington\u27s disease (HD) is an autosomal dominant neurodegenerative disease whose predominant ne...
Aims: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease-modifying treatm...
Huntington's disease (HD) is a dominant neurodegenerative disorder caused by expansion of a CAG repe...
<p>Huntington’s disease (HD) is an adult-onset, neurodegenerative disease caused by an autosomal dom...
Huntingtin protein (Htt) is ubiquitously expressed, yet Huntington’s disease (HD), a fatal neurologi...
Huntington’s disease (HD) is a genetic neurodegenerative disorder caused by expansion of a CAG repea...
Huntington’s disease (HD) is the most common dominantly-inherited neurodegenerative disease and affe...
Huntington disease (HD) results from polyglutamine expansion in the huntingtin protein (htt). Despit...
Huntington's disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and p...
<div><p>Huntington’s disease (HD) is a fatal neurodegenerative disease, characterized by motor defec...
Huntington’s Disease is an adult-onset dominant heritable disorder characterized by progressive psyc...
BackgroundHuntington's disease (HD) is a progressive neurodegenerative disorder associated with agin...
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation i...
Huntington’s disease (HD) is caused by the expansion of a CAG repeat in the huntingtin (HTT) gene. T...
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuro...
Huntington\u27s disease (HD) is an autosomal dominant neurodegenerative disease whose predominant ne...
Aims: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease-modifying treatm...
Huntington's disease (HD) is a dominant neurodegenerative disorder caused by expansion of a CAG repe...
<p>Huntington’s disease (HD) is an adult-onset, neurodegenerative disease caused by an autosomal dom...
Huntingtin protein (Htt) is ubiquitously expressed, yet Huntington’s disease (HD), a fatal neurologi...
Huntington’s disease (HD) is a genetic neurodegenerative disorder caused by expansion of a CAG repea...
Huntington’s disease (HD) is the most common dominantly-inherited neurodegenerative disease and affe...
Huntington disease (HD) results from polyglutamine expansion in the huntingtin protein (htt). Despit...