Heat map of the top 35 genes with the most variable read counts in the dataset.

<p>The bar along the top of the plot highlights the mediators in which the gene counts varied. This is also reinforced in the names on the x-axis, which show the treatment and mediator in which the genes (Y-axis) showed high variation. CTL = Control samples; VR = VR-2332 PRRSV strain; HP = High pathogenic strain rJXwn06. The plot showed possible candidates for the genes that appear to impact PRRSV pathogenesis based upon the contrasts. One particular gene from this list, the proteoglycan <i>DCN</i>, was also show to be highly variable across treatments based upon normalized fold change. The gene <i>DCN</i> also appeared multiple times in the predicted networks analysis as part of a group of differentially expressed proteoglycans shown to be related damage associated molecular pattern signaling.