AHCC increases apoptosis in most AML cell lines.

<p>The AML cell lines OCI-AML3 (left panels, 1 x 10⁶ cells/ml), MOLM-13 (middle panels, 1 x 10⁶ cells/ml) and THP-1 (right panels, 1 x 10⁶ cells/ml) were treated with 0, 1, 5 or 10 mg/ml of AHCC for 24 or 48 hours. (A). Trypan Blue Exclusion was done to measure viability (n = 3 separate experiments). (B). The 3 respective cell lines were treated as above and Annexin V / Propidium Iodide (PI) staining was measured using flow cytometry (n = 3 separate experiments). * p≤0.05.