Activation of receptor tyrosine kinases (RTK).

<p>Heatmap representing the relative spot intensity for the 39 activated receptors and the four DRG conditions quantified from the X-ray films and representative image of the X-ray film, highlighting the most phosphorylated receptors. The graphic represents the mean spot intensity of the most phosphorylated receptors in retrieved and <i>in vitro</i> embryonic and adult DRG, showing the three different families: epidermal-growth factor receptors (EGFR), platelet-derived growth factor (PDGF) receptor alpha and tropomyosin receptor kinase A (TrkA) receptor. For the array analysis, the protein lysate from a pull of 6–10 DRG for each condition (eDRG and aDRG; retrieved and <i>in vitro</i>), from three independent experiments (n = 3), was collected. One array was used per condition.