DENV DI/DII induces poorly-neutralising, highly-enhancing cross-reactive antibodies.
- Jose L. Slon Campos (4276216)
- Monica Poggianella (776181)
- Sara Marchese (4276219)
- Monica Mossenta (4276213)
- Jyoti Rana (4276222)
- Francesca Arnoldi (87304)
- Marco Bestagno (208268)
- Oscar R. Burrone (126517)
Publication date
July 2017
DOIAbstract
<p>A) Neutralisation and ADE of all four DENV serotypes, ZIKV, WNV and YFV, with DENV anti-3DI/DII and anti-4DI/DII pooled sera (in all cases, n = 3 for each virus-sera combination). B) FRNT<sub>50</sub> titres, as determined in (A), * indicates FRNT<sub>50</sub> titres below detection limit of the assay (≥25).</p