Two immune profiles of ALS patients reveal significant phenotypic differences.

<p>Leukocyte phenotypes from HVs and ALS patients sub-grouped into Profiles 1 and 2 were compared. <b>A.</b> Box-and-whisker plots of total white blood cells (WBCs) and mononuclear cells (MNCs) are shown. The boxes indicate the 25-75^th percentile, the horizontal line indicates the median, and the whiskers represent minimum and maximum values. <b>B.</b> Pie graphs depicting the peripheral blood leukocyte compartment of the three groups. The HV pie graph was set to 100% and the other pie graphs were sized in relation to the HV. <b>C.</b> Box-and-whisker plots of immunophenotypes associated with principal components. *** = p value <0.001, and * = p value <0.05.