Select chromosome-wide scans for epistatic effects in GEUVADIS data set.

<p>Depicted are the −log₁₀(<i>P</i>) transformed MAPIT p-values of quality-control-positive <i>cis</i>-SNPs plotted against their genomic position in chromosomes (A) 1, (B) 6, and (C) 22, respectively. Note that MAPIT was implemented with <b>K</b>_<i>cis</i>. Here, the epistatic associated genes are labeled (blue). The (red) horizontal line indicates a genome-wide significance threshold (<i>P</i> = 1.828 × 10⁻⁸). Note that all panels are truncated at −log₁₀(<i>P</i>) = 10 for consistency and presentation, although for some genes there are strongly marginally epistatic associated markers with p-values <i>P</i> ≈ 0.