Enhanced <i>Ccl24</i>, myeloid cells and <i>Il4</i>^<i>GFP+</i> Th2 cell infiltration in <i>Map3k8</i>^{<i>–/–</i>}mice.

<p>A) Representative FACS profile for CD11c⁺ CD11b⁺ cells from the intestinal LP of D5 <i>H</i>. <i>polygyrus</i> infected WT and <i>Map3k8</i>^{<i>–/–</i>}mice. B) <i>Ccl24</i> and <i>Ear11</i> expression from CD11c⁺ CD11b⁺ cells D5 <i>H</i>. <i>polygyrus</i> infected WT and <i>Map3k8</i>^{<i>–/–</i>}mice. C-H) Frequency and number of (C) eosinophils (live/CD45⁺/SiglecF⁺/SSChi); (D) neutrophils (live/CD45⁺/SiglecF^-/CD11b⁺/Ly6G⁺); (E) monocytes (live/CD45⁺/SiglecF^-/CD11b⁺/Ly6G^-/Ly6C⁺); (F) <i>Il4</i>^<i>GFP+</i> Th2 cells (live/CD45⁺/CD4⁺/CD3⁺/TCRβ⁺/<i>Il4</i>^<i>GFP+</i>) in the intestinal LP of D5 <i>H</i>. <i>polygyrus</i> infected WT and <i>Map3k8</i>^{<i>–/–</i>}mice. Data from B) is representative of 2 independent experiments with 3 biological replicates per group. Data from C-H) is representative of 2 independent experiments with 5–6 mice/group. * and ** denotes p≤0.05 using Mann-Whitney test.