<p>A) Megakaryocyte DNA content in PKCε<sup>-/-</sup> and PKCε<sup>+/+</sup> bone marrow cultured in the presence of 50 ng/mL TPO. B) Megakaryocyte number is cultured bone marrow from PKCε<sup>-/-</sup> and PKCε<sup>+/+</sup> mice supplemented with 50 ng/mL TPO. * p < 0.05 compared to PKCε<sup>+/+</sup>, n = 7.</p
Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets ...
In vitro assays for the study of human megakaryocyte (Mk) progenitor cells have been compromised by...
Thrombopoietin (TPO) is widely used for ex vivo expansion of hematopoietic stem cells. Previously, w...
<p>(A) The experiment outline used in bone marrow (BM) experiments. Flow cytometry analysis using mo...
<p>(A) <i>In vitro</i> MK maturation. Lin<sup>-</sup> bone marrow cells (5×10<sup>4</sup> cells/cham...
<p>Megakaryocytes from a decalcified femur (A) and from a bone marrow culture (B). Because the numbe...
<p>A) Western blot analysis of PKCε, PKCα, and PKCδ in PKCε<sup>+/+</sup> and PKCε<sup>-/-</sup> mou...
Background aims. Platelet transfusion can be a life-saving procedure in different medical settings. ...
The proliferation, differentiation and maturation of haematopoietic progenitor cells into megakaryoc...
Little is known concerning the interaction of thrombopoietin (TPO) with other megakaryocyte-active c...
peer reviewedTo assess the variation of thrombopoietin (TPO) responsiveness associated with megakary...
poster abstractEmerging evidence demonstrates that megakaryocytes (MK) play a key role in regulatin...
Increasing the number of megakaryocytic cells in stem cell transplants by ex vivo expansion culture ...
Specialized bone marrow microenvironments (vascular and osteoblastic 'niches') regulate normal haema...
Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeos...
Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets ...
In vitro assays for the study of human megakaryocyte (Mk) progenitor cells have been compromised by...
Thrombopoietin (TPO) is widely used for ex vivo expansion of hematopoietic stem cells. Previously, w...
<p>(A) The experiment outline used in bone marrow (BM) experiments. Flow cytometry analysis using mo...
<p>(A) <i>In vitro</i> MK maturation. Lin<sup>-</sup> bone marrow cells (5×10<sup>4</sup> cells/cham...
<p>Megakaryocytes from a decalcified femur (A) and from a bone marrow culture (B). Because the numbe...
<p>A) Western blot analysis of PKCε, PKCα, and PKCδ in PKCε<sup>+/+</sup> and PKCε<sup>-/-</sup> mou...
Background aims. Platelet transfusion can be a life-saving procedure in different medical settings. ...
The proliferation, differentiation and maturation of haematopoietic progenitor cells into megakaryoc...
Little is known concerning the interaction of thrombopoietin (TPO) with other megakaryocyte-active c...
peer reviewedTo assess the variation of thrombopoietin (TPO) responsiveness associated with megakary...
poster abstractEmerging evidence demonstrates that megakaryocytes (MK) play a key role in regulatin...
Increasing the number of megakaryocytic cells in stem cell transplants by ex vivo expansion culture ...
Specialized bone marrow microenvironments (vascular and osteoblastic 'niches') regulate normal haema...
Emerging evidence demonstrates that megakaryocytes (MK) play key roles in regulating skeletal homeos...
Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets ...
In vitro assays for the study of human megakaryocyte (Mk) progenitor cells have been compromised by...
Thrombopoietin (TPO) is widely used for ex vivo expansion of hematopoietic stem cells. Previously, w...