Temporal correlations of low-frequency blood-oxygen-level-dependent (BOLD) signals are associated with cognitive performance in moyamoya disease.

<p>Associations of temporal correlations of low-frequency BOLD signals with perceptual organization (a), working memory (b) and processing speed (c) were explored, and significant associations were overlaid on a 3D template in MNI space (p < 0.001, uncorrected). The circles show brain areas that have statistically significant functional connections. The color bar indicates t statistics. A. Perceptual organization (PO) scores are associated with connections between the visual area, visual association area, and prefrontal association area. The scatter plot shows the representative correlations between connectivity of the left hippocampus/right inferior occipital region and PO scores (r = 0. 65, p < 0.001). b.Working memory (WM) is associated with multiple connections among the visual area, visual association area, and prefrontal association area. The scatter plot shows representative correlations between connectivity of the left hippocampus/right inferior occipital region and PS scores (r = 0. 76, p < 0.001). c. Processing speed (PS) is associated with multiple connections between the visual area, visual association area, and prefrontal association area. The scatter plot shows representative correlations between connectivity of the left hippocampus/right inferior occipital region and PS scores (r = 0. 72, p < 0.001).