Histopathology of tissues infected with <i>Salmonella</i> Typhimurium.

<p>Hematoxylin and eosin-stained sections of liver, colon, ileum and mesenteric lymph node (MLN) from rhesus macaques. The images in the left (10X magnification) and middle (20X magnification) columns are from animals infected with <i>Salmonella</i> Typhimurium I77 (ST19). Images on the right (20X magnification) are from animals infected with <i>Salmonella</i> Typhimurium D65 (ST313). Areas of necrosis and lymphocytic infiltration of the liver section from a ST19-infected animal are indicated by arrows. Tissue sections from a ST19-infected animal show areas of erosion of mucosal epithelium of the colon and ileum combined with areas of infiltration of lymphocytes and plasma cells. These areas are indicated by arrows. Granulomatous areas consisting of multinucleated giant cells in the mesenteric lymph node of the animal infected with ST19 are indicated by arrows. All sections from D65-infected animals display essentially normal histology.