CTL promiscuity for epitope variant recognition.

<p>Top panel: The mean ΔRE values of all variants in the virus library are plotted for each epitope, excluding those with mutations in the epitope flanking residues. The numbers and frequencies (over all variants adequately represented in the virus library) of variants achieving a threshold of ΔRE≥0.7 are indicated. Bottom panel: The numbers of variants in different ranges of mean ΔRE values are indicated.