Weight gain, visceral adiposity, and plasma glucose.

<p>Wild type (Wt), myeloid IKKβ deficient (<i>IkbkbΔmye</i>), or hepatocyte IKKβ deficient (<i>IkbkbΔhep</i>) mice in both genders, were fed regular chow (Control) or high cholesterol and saturated fat diet (HCFD) from 2.5 months of age for 20 weeks, and body weight gain (A) and visceral adiposity weight (B) were determined. Visceral adiposity was determined by summing the individual measures of epidydimal/gonadal fat, mesenteric fat, and retroperitoneal fat. Glucose tolerance (C) and insulin sensitivity (D) tests were also performed after overnight fast. *p<0.05, **p<0.01, ***p<0.001 compared to Control diet within gender and within genotype by t-test. †p<0.05, ††p<0.01 compared to other genotype within gender and within diet by ANOVA and post-hoc Tukey test.